[Lys(Ac)18]-Histone H3 (1-21)-GGK(Biotin)-NH2 – 1 mg

Name: [Lys(Ac)18]-Histone H3 (1-21)-GGK(Biotin)-NH2 | AnaSpec
SKU: AS-64638-1
Price: 453.00 USD
Availability: InStock

$453.00

[Lys(Ac)18]-Histone H3 (1-21)-GGK(Biotin)-NH2, Histone H3 aa residues 1-21, acetylated at lysine 18, C-terminal GG linker followed by biotinylated lysine.

SKU: AS-64638-1 Category: Peptides Tags: biotin, histones, peptides

Description
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Overview

The [Lys(Ac)18]-Histone H3 (1-21)-GGK(Biotin)-NH2 is a specialized peptide that consists of the first 21 amino acid residues of Histone H3, specifically acetylated at lysine 18. This peptide features a C-terminal GG linker followed by a biotinylated lysine, making it an essential tool for researchers studying histone modifications and their implications in cancer prognosis. As the acetylation of histone H3 at lysine 18 is closely linked to predicting prostate cancer recurrence and clinical outcomes in patients with lung and kidney cancers, this peptide can significantly support investigations in cancer biology.

Manufactured with >95% peptide purity, the [Lys(Ac)18]-Histone H3 (1-21)-GGK(Biotin)-NH2 is provided as a lyophilized powder. It is reconstituted in distilled water at a concentration of 1 mg/ml, ensuring easy handling for your experiments. Whether you’re involved in basic research or clinical applications, you’ll find this biotinylated peptide is a valuable addition to your research toolkit.

Key Features

Composed of Histone H3 amino acid residues 1-21
Acetylated at lysine 18 for specific research applications
C-terminal GG linker enhances stability
Biotinylated for versatile labeling and detection
Available in a lyophilized powder format for easy reconstitution

Specifications

Item	Details
Product Name	[Lys(Ac)18]-Histone H3 (1-21)-GGK(Biotin)-NH2
Purity	>95%
Concentration	1 mg/ml (after reconstitution)
Format	Lyophilized powder

FAQ

What is the significance of lysine 18 acetylation?

Acetylation at lysine 18 of Histone H3 is a key modification associated with gene regulation and is often studied in the context of cancer research, particularly for predicting patient outcomes.

How do I reconstitute this peptide?

To reconstitute [Lys(Ac)18]-Histone H3 (1-21)-GGK(Biotin)-NH2, dissolve the lyophilized powder in distilled water to achieve the desired concentration, such as 1 mg/ml.