MBP, MAPK Substrate, Biotinylated, Phosphorylated [Biotin-APR-pT-PGGRR] – 1 mg

Name: MBP, MAPK Substrate, Biotinylated, Phosphorylated | AnaSpec
SKU: AS-29877
Price: 334.00 USD
Availability: InStock

$334.00

This is an N-terminally biotinylated peptide, with a phosphorylated Thr97. The sequence APRTPGGRR contains a native sequence derived from bovine myelin basic protein amino acids 95-98 (PRTP). The rest of the sequence is not derived from a native sequence, but is a synthetic construct.

SKU: AS-29877 Category: Peptides Tags: biotinylated peptides, MAPK substrates, Phosphorylated Peptides

Description
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Overview

The MBP, MAPK Substrate, Biotinylated, Phosphorylated [Biotin-APR-pT-PGGRR] is a highly specialized peptide designed for researchers focusing on MAP kinase activity. This N-terminally biotinylated peptide features a phosphorylated threonine at position 97 within the sequence APRTPGGRR, derived from the bovine myelin basic protein. The design includes a native sequence from the PRTP region (amino acids 95-98), alongside a synthetic construct that enhances its specificity for p44MAPK (ERK1) and p42MAPK (ERK2). With its consensus sequence Pro-X-(Ser/Thr)-Pro, this peptide is an essential tool for studying MAP kinase signaling pathways and their physiological implications.

Key Features

N-terminally biotinylated for easy detection and labeling
Phosphorylated at Thr97 to mimic biological conditions
Specifically targets MAP kinases p44MAPK and p42MAPK
Includes a consensus sequence recognized by MAP kinases
Suitable for a variety of applications in biochemical research

Specifications

Product	Content
Product Name	MBP, MAPK Substrate, Biotinylated, Phosphorylated
Sequence	APRTPGGRR
Modification	Biotinylated, Phosphorylated
Weight	1 mg

FAQ

What are the applications of this peptide?

This biotinylated and phosphorylated peptide is primarily used in research involving MAP kinase pathways, helping to study cellular signaling, drug responses, and disease mechanisms.

How should I store this peptide?

The MBP, MAPK substrate peptide should be stored at -20 °C to maintain its integrity and effectiveness. Avoid repeated freeze-thaw cycles to preserve its properties.

Can this substrate be used in competitive inhibition assays?

Yes, due to its specific sequence, the peptide can be effectively employed in competitive inhibition assays to study MAP kinase activity and its modulators.

If you are in the market for quality peptides and substrates, consider exploring our broader collection of peptides and related products, including other MAPK substrates such as PKG Substrate [RKRSRAE] and Autocamtide-2 [KKALRRQETVDAL]. Each product is designed to help you achieve precise results in your research.