[pSer10]-Histone H3 (1-21)-GGK(Biotin)-NH2 – 1 mg

Overview

The [pSer10]-Histone H3 (1-21)-GGK(Biotin)-NH2 is a valuable peptide product that plays a critical role in research involving epigenetics and chromosome dynamics. This peptide comprises amino acid residues 1 to 21 of Histone H3, specifically phosphorylated at Ser10, showcasing its importance as a mitotic marker associated with chromosome condensation. With its C-terminal GG linker followed by a biotinylated lysine, this product facilitates the study of protein interactions, modifications, and functions.

Key Features

• High purity: >95% peptide purity ensures reliable results in your experiments.
• Biotinylated: The incorporation of biotin allows for easy detection and isolation using streptavidin-based methods.
• Specific phosphorylation: The attachment of phosphate at Ser10 enables the study of critical cellular processes during mitosis.
• Convenient form: Delivered as a lyophilized powder, it’s easy to store and reconstitute.
• Versatile applications: Ideal for use in applications such as Western blotting, immunoprecipitation, and protein-protein interaction studies.

Specifications

FAQ

What is the significance of the phosphorylation at Ser10?

The phosphorylation at Ser10 of Histone H3 is a well-known mitotic marker, indicating active mitosis and chromosome condensation. This makes it indispensable for research focused on cell division and chromatin dynamics.

How should I store this peptide?

Store the lyophilized powder at -20°C. Once reconstituted, keep it at -80°C for long-term storage to maintain its integrity and activity.

Can I use this peptide for protein labeling?

Yes, the biotinylated nature of this peptide allows for easy labeling with streptavidin, making it suitable for various assays and detection methods. For similar applications, consider exploring our PKG Substrate and Autocamtide-2.

For those interested in protein-protein interactions, our CREBtide can provide useful insights as well.

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