SensoLyte® 520 TACE (a-Secretase) Activity Assay Kit Fluorimetric – 1 kit
$642.00
TACE (tumor necrosis factor-alpha converting enzyme), α-secretase, or ADAM17 is a member of the ADAM family of proteases that contain both disintegrin and metalloprotease (catalytic) domains.
Overview
The SensoLyte® 520 TACE (α-Secretase) Activity Assay Kit is designed to measure the enzymatic activity of TACE, also known as tumor necrosis factor-alpha converting enzyme or ADAM17. This assay kit provides you with a sensitive and reliable way to monitor the activity of TACE in various biological samples, making it an essential tool for research focused on cell signaling, inflammation, and neurobiology.
TACE plays a significant role in several physiological processes, including sperm-egg binding, muscle cell fusion, and the modulation of Notch signaling, highlighting its importance in developmental biology and immune response. Researchers are increasingly investigating TACE as a potential target for anti-inflammatory therapies, making this assay kit indispensable for those exploring new therapeutic avenues.
Key Features
- Fluorimetric detection method for increased sensitivity
- Suitable for a variety of biological samples
- Comprehensive protocol included for straightforward application
- Supports research in neurogenesis and inflammatory response
- Compatible with high-throughput screening
Specifications
| Product Name | SensoLyte® 520 TACE Activity Assay Kit |
| Assay Type | Fluorimetric |
| Sample Types | Cell lysates, tissues |
| Kit Size | 1 kit |
FAQ
What is TACE’s primary function?
TACE, or Tumor Necrosis Factor-alpha Converting Enzyme, primarily cleaves pro-TNFα to release the active cytokine, playing a key role in inflammation and immune response.
Can this assay be used for high-throughput analysis?
Yes, the SensoLyte® 520 TACE Activity Assay Kit is designed for compatibility with high-throughput screening, allowing for efficient analysis of multiple samples.
What types of samples can I use with this assay kit?
This kit is suitable for analyzing samples from cell lysates and tissues, making it versatile for various research applications.
For additional assays, consider exploring our SensoLyte® Anti-Human MOG (1-125) Mouse IgG Specific ELISA Kit or our SensoLyte® Anti-PLP (178-191) IgG Quantitative ELISA Kit for comprehensive insights into your research.
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