TAT (47-57) GGG-Cys(Npys) – 1 mg

Overview

The TAT (47-57) GGG-Cys(Npys) peptide is an essential tool for researchers working in molecular biology and biochemistry. This specific peptide fragment, derived from the HIV transactivator protein (TAT), is known for its unique ability to penetrate cell membranes directly, bypassing endocytosis. With a linker GGG (Gly-Gly-Gly) at the C-terminal end and an activated cysteine residue (C(Npys)), this peptide is engineered for superior performance in various applications, including protein labeling and cell targeting.

Key Features

• Direct plasma membrane penetration due to its arginine-rich sequence.
• Incorporates a GGG linker for enhanced stability and performance.
• Utilizes the 3-Nitro-2-pyridinesulfenyl (Npys) group for effective thiol activation.
• Ideal for use in conjugation reactions and cellular delivery systems.
• Available in 1 mg quantities for varied research needs.

Specifications

FAQ

What is the TAT (47-57) peptide used for?

This peptide is primarily used in research settings for studying protein transduction and as a carrier for drug delivery systems. Its ability to penetrate cell membranes makes it an excellent choice for targeting specific cellular components.

How does the Npys modification enhance performance?

The Npys (3-Nitro-2-pyridinesulfenyl) group allows for rapid reaction when introduced to a thiol group. This modification improves the specificity and efficiency of conjugation reactions, making it ideal for labeling applications.

Can I use this peptide for labeling proteins?

Yes, the TAT (47-57) peptide can be effectively used in protein labeling, especially when combined with other reagents from our catalog, such as our PKG Substrate or Autocamtide-2. This peptide enhances cellular uptake and target specificity.

For all your peptide needs, explore our extensive collection of peptides to find the perfect match for your research.

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