Nuclear Factor (Erythroid-derived 2) like 2, Nrf2 (74-87) – 5 mg

Overview

Nuclear Factor (Erythroid-derived 2) like 2, Nrf2 (74-87) is a specialized peptide crucial in regulating the expression of antioxidative and cytoprotective genes. Derived from the Neh2 domain of Nrf2, this peptide showcases the unique DxETGE motif, which plays an essential role in binding the Keap1 Kelch adaptor protein. By displacing Nrf2 from Keap1, it activates the transcription factor, leading to the expression of defensive genes that protect cells from oxidative stress.

Key Features

• Enhances the activation of Nrf2, increasing the expression of protective genes.
• Derived from the Neh2 domain, ensuring specificity and functionality.
• Facilitates research into antioxidative mechanisms and cellular responses.
• Available in a 5 mg vial, suitable for various experimental applications.
• Compatible with our other peptide offerings, enhancing your research capabilities.

Specifications

FAQ

What is the role of Nrf2 in the body?

Nrf2 is a transcription factor that plays a significant role in cellular defense mechanisms by regulating genes involved in antioxidative and cytoprotective responses, helping maintain cellular health.

How do I use Nrf2 (74-87) in my research?

This peptide can be utilized in cellular assays to investigate the activation pathways of Nrf2 and its impact on gene expression related to oxidative stress and cytoprotection.

Can I combine Nrf2 (74-87) with other peptides?

Yes, Nrf2 (74-87) can be effectively combined with various peptides, such as PKG Substrate and Autocamtide-2. This can help broaden your experimental framework and insights.

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