PLP (139-151) C140S – 1 mg

Overview

The PLP (139-151) C140S peptide is an essential tool for researchers investigating the mechanisms of acute experimental allergic encephalomyelitis (EAE), particularly in the SJL mouse model. This specific serine-substituted variant of the PLP peptide has been shown to induce severe EAE, making it a vital resource for understanding immune responses and neurological conditions. Whether you’re conducting basic research or exploring therapeutic avenues, this peptide is an excellent addition to your laboratory’s collection.

Key Features

• Induces acute experimental allergic encephalomyelitis in SJL mice
• High purity and quality for reliable experimental results
• Useful for studies in immunology and neurobiology
• Available in a convenient 1 mg quantity
• Part of a comprehensive range of peptides and assay kits

Specifications

FAQ

What is the significance of the C140S substitution?

The serine substitution at position 140 alters the peptide’s structure, which has been shown to enhance its ability to induce EAE in SJL mice, making it an important tool for studying this model of autoimmune disease.

How should I store the PLP (139-151) C140S peptide?

For optimal stability, store the peptide at -20°C. It’s recommended to keep it protected from light and moisture to maintain its integrity.

Can this peptide be used in other models besides SJL mice?

While this peptide is primarily studied in SJL mice due to its specific effects, further research may explore its application in other animal models to broaden the understanding of its immunological impacts.

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