Biotin-Exendin 4

Name: Buy Biotin-Exendin 4 | AnaSpec
SKU: biotin-exendin-4-b45c32ed-1118-42c9-acd7-2f92435c1f9c
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Exendin 4 an agonist of glucagon-like peptide 1 (GLP-1) receptor, induces release of insulin after food intake. This peptide has biotin on the N-terminus.

Size

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SKU: biotin-exendin-4-b45c32ed-1118-42c9-acd7-2f92435c1f9c Category: Peptides Tags: GLP-1, insulin, peptides

Overview

Biotin-Exendin 4 offers a powerful approach to understanding insulin release in response to food intake. This synthetic peptide is a potent agonist of the glucagon-like peptide 1 (GLP-1) receptor, stimulating insulin secretion for effective glucose management. Biotin-Exendin 4 is especially notable for its biotin modification at the N-terminus, enhancing its versatility in research and diagnostic applications.

Key Features

Agonist of the GLP-1 receptor, promoting insulin secretion
Biotin modification for easy detection and labeling
Longer half-life than GLP-1, increasing potency
Derived from the Gila monster, Heloderma suspectum
53% sequence homology with GLP-1

Specifications

Property	Details
Peptide Name	Biotin-Exendin 4
Origin	Gila monster (Heloderma suspectum)
Modification	Biotin at N-terminus

FAQ

What role does Exendin 4 play in insulin release?

Exendin 4 acts as an agonist for the GLP-1 receptor, which is crucial for stimulating insulin secretion after meals, contributing to better glucose control.

How does the biotin modification benefit research?

The biotin modification at the N-terminus allows for convenient labeling and detection in various assays, facilitating the study of GLP-1 related pathways.

What makes Biotin-Exendin 4 different from GLP-1?

Biotin-Exendin 4 has a longer half-life in plasma compared to GLP-1, which enhances its effectiveness as an insulinotropic agent, making it a valuable tool in metabolic research.

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