[Lys(Ac)12/16, Lys(Me3)20]-Histone H4 (1-25)-GSGSK(Biotin) – 1 mg

Overview

The [Lys(Ac)12/16, Lys(Me3)20]-Histone H4 (1-25)-GSGSK(Biotin) is an advanced peptide designed for research in epigenetics and gene regulation. This peptide features specific acetylation at Lys12 and Lys16, and trimethylation at Lys20, making it essential for studying histone modifications and their effects on transcriptional activity. The biotinylated GSGS linker enhances the binding capabilities for various applications, allowing for effective labeling and detection in your experiments.

Key Features

• Acetylated at Lys12 and Lys16, trimethylated at Lys20
• Biotinylated C-terminal GSGS linker for easy detection
• Designed for studies involving transcriptional silencing and heterochromatin formation
• Facilitates protein-protein interactions and binding specificity
• Ideal for use in various assay kits and protein labeling experiments

Specifications

FAQ

What is the significance of the modifications on this peptide?

The acetylation at Lys12 and Lys16, along with trimethylation at Lys20, are critical for regulating gene expression by influencing chromatin structure. These modifications play a key role in the formation of heterochromatin and transcriptional silencing.

How can I use this peptide in my research?

This histone peptide can be utilized in various assays for studying protein interactions, histone modifications, and gene regulation. You can incorporate it into your experiments for precise labeling and detection, enhancing your understanding of epigenetic mechanisms.

Is this peptide suitable for in vivo studies?

While this peptide is primarily designed for in vitro applications, researchers have used biotinylated peptides for in vivo studies with appropriate controls. The biotin tag facilitates purification and detection methods in living systems.

Explore our complete range of peptidesincluding our PKG Substrate and Autocamtide-2 products, to enrich your experimental toolkit. The [Lys(Ac)12/16, Lys(Me3)20]-Histone H4 (1-25)-GSGSK(Biotin) is a valuable addition to assist you in your groundbreaking research. Don’t miss the chance to enhance your studies with this essential peptide.

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