Overview
Fmoc-4-azidophenylalanine is an exceptional amino acid utilized in Solid Phase Peptide Synthesis (SPPS), making it ideal for the creation of photoreactive affinity labels. This amino acid features a stable azido (N3) side-chain group that withstands the rigorous conditions of chemical reactions, specifically in the presence of trifluoroacetic acid (TFA) or piperidine (Pip), which are frequently used in SPPS. The azido group can be easily converted to an amine, either on the solid phase or in solution, through a simple Staudinger reduction process.
This unique amino acid allows researchers and chemists to create highly specific and effective photoreactive agents, broadening the applications in fields ranging from biochemical research to therapeutic development. Whether you’re working on targeted drug delivery systems or creating complex peptide structures, Fmoc-4-azidophenylalanine will prove to be a valuable addition to your toolkit.
To enhance your peptide synthesis projects, consider pairing it with our other specialty reagents, such as 2S-N-Fmoc-5-azido-pentanoic acid or Fmoc-Lys(N3)-OHwhich complement the properties of Fmoc-4-azidophenylalanine.
Key Features
- Stable azido side-chain group ensures reliability during synthesis.
- Facilitates the production of photoreactive affinity labels.
- Compatible with standard SPPS protocols.
- Effortless conversion to amine through Staudinger reduction.
- Ideal for use in various biochemical applications.
Specifications
| Item | Details |
|---|---|
| Name | Fmoc-4-azidophenylalanine |
| Category | Azide and Alkyne containing Amino Acids |
| Form | Powder |
| Purity | ≥ 95% |
| Molecular Weight | 284.28 g/mol |
FAQ
What applications can Fmoc-4-azidophenylalanine be used for?
This amino acid is primarily utilized in the synthesis of photoreactive affinity labels, making it suitable for applications in drug development, diagnostic assays, and various biochemical assays.
How does the azido group perform in Solid Phase Peptide Synthesis?
The azido group remains stable during the synthesis process, allowing for reliable incorporation into peptides without compromising the integrity of the molecule.
Can I find related products for my peptide synthesis?
Yes, we offer a range of complementary products, including Azide and Alkyne containing Amino Acids that can enhance your research and synthesis projects.
Invest in Fmoc-4-azidophenylalanine today and elevate your peptide synthesis capabilities. Shop now and discover the potential of this remarkable amino acid.




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