Fmoc-Lys(N3)-OH

Overview

Fmoc-Lys(N3)-OH is an innovative and unusual amino acid specifically designed for Solid Phase Peptide Synthesis (SPPS). Its unique azido (N3) side-chain group provides a stable solution during the synthesis of modified peptides and proteins. Common reagents in SPPS, such as trifluoroacetic acid (TFA) and piperidine (Pip), don’t compromise the stability of the azido group, making it an excellent choice for researchers looking to develop complex biomolecules.

Key Features

• Stable azido group in TFA and Pip
• Facilitates side-chain modifications
• Allows for easy Staudinger reduction to amine
• Ideal for peptide and protein synthesis
• Versatile applications in biomedical research

Specifications

FAQ

What is Fmoc-Lys(N3)-OH used for?

Fmoc-Lys(N3)-OH is primarily used in peptide synthesis, particularly for introducing side-chain modifications in peptides and proteins. Its azido group enables further chemical modifications via reactions like Staudinger reduction.

How does the stability of Fmoc-Lys(N3)-OH compare with other amino acids?

This amino acid maintains stability in conditions typically used in peptide synthesis, such as TFA and Pip, making it a reliable option alongside traditional amino acids.

Can Fmoc-Lys(N3)-OH be used in synthesizing labeled proteins?

Yes, Fmoc-Lys(N3)-OH can be crucial in synthesizing labeled proteins by allowing for specific modifications that are essential in biochemical research.

To enhance your research capabilities, consider browsing related products such as 2S-N-Fmoc-5-azido-pentanoic acid and Fmoc-4-azidophenylalanine for additional azide-containing amino acids. Explore our complete range of Azide and Alkyne containing Amino Acids to find the perfect match for your peptide synthesis needs.

Related Products

• TBTA, Tris[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl] amine