[Gly21]-beta-Amyloid (1-42), Dutch Mutation – 0.5 mg

Overview

Understanding the role of beta-amyloid in Alzheimer’s disease is crucial for research and therapeutic development. The [Gly21]-beta-Amyloid (1-42), Dutch Mutation is a significant peptide that plays a role in the pathology of autosomal dominant Alzheimer’s disease. This particular mutation, also known as A21G, is distinct because it shows a lower tendency to aggregate in the brain, which is unlike other familial forms of Alzheimer’s. Peculiarly, the deposits mainly consist of A-beta 1-40 rather than the more commonly studied A-beta 1-42. Researchers looking for detailed and accurate assay kits for studying Alzheimer’s will find this peptide essential for their work.

Key Features

• High-quality peptide to study Alzheimer’s disease
• Unique low aggregation tendency
• Essential for research into beta-amyloid pathology
• 0.5 mg concentration for extensive experimental use
• Supports a deeper understanding of familial Alzheimer’s

Specifications

FAQ

What is the significance of the Dutch mutation in Alzheimer’s research?

The Dutch mutation, or A21G, is significant because it leads to unique pathological features in Alzheimer’s disease that provide insights into the mechanisms of amyloid deposition and potential treatment avenues.

How does the aggregation tendency of this peptide compare with others?

This peptide is notable for its lower aggregation propensity, which allows researchers to study its behavior and interactions in a less aggregated state, thus providing clearer insights into its biological role.

Can this peptide be used in combination with other assays?

Yes, researchers can use the [Gly21]-beta-Amyloid alongside other peptides and substrates, such as our PKG Substrate and Autocamtide-2to gain a comprehensive understanding of amyloid pathology.

For those involved in neurological research and looking to procure valuable peptides, the [Gly21]-beta-Amyloid (1-42), Dutch Mutation represents an opportunity to enhance your studies and broaden your understanding of Alzheimer’s disease. Purchase this peptide now and enrich your research.

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