Overview
The HIF-1a (556-574) peptide is a critical 19-mer fragment of the hypoxia-inducible factor-1 alpha (HIF-1a). As a master regulator of oxygen homeostasis, this peptide plays a pivotal role in the body’s response to low oxygen conditions. When the oxygen levels drop, the HIF-1a subunit becomes stabilized, initiating the expression of hypoxia-induced genes. It is essential in the binding process to the von Hippel-Lindau factor (VHL), a key E3 ubiquitin ligase, with proline 564 being crucial for this interaction. Purchase the HIF-1a (556-574) peptide for innovative research and accurate assay development.
Key Features
- High purity peptide for reliable results
- Essential for studying hypoxia in cellular environments
- Supports research in oxygen homeostasis and related pathways
- Facilitates binding studies with VHL
- Useful in various applications, including protein labeling and peptide enzyme substrates
Specifications
| Property | Details |
|---|---|
| Catalog Number | HIF-1a (556-574) |
| Form | Lyophilized powder |
| Size | 1 mg |
| Purity | ≥ 95% |
FAQ
What applications is the HIF-1a (556-574) peptide suitable for?
This peptide is ideally suited for studies related to hypoxia and oxygen regulation. It’s often used in protein labeling and peptide enzyme substrate research.
How should I store the HIF-1a (556-574) peptide?
Store the peptide at -20°C and ensure it remains protected from moisture and light to maintain its integrity.
Can the HIF-1a peptide be used in cell culture experiments?
Yes, the HIF-1a (556-574) peptide is suitable for cell culture experiments, especially those focused on hypoxic conditions and cellular responses to low oxygen levels.
If you’re looking for high-quality peptides that support your research needs, explore our broad range of peptidesincluding the innovative PKG Substrate and the versatile Autocamtide-2.




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