Overview
The HIV Substrate, HiLyte™ Fluor 488 represents a crucial tool in HIV research, specifically designed to study HIV-1 protease activity. This peptide substrate is derived from the native p17/p24 cleavage site integral to the HIV precursor polyprotein Prgag, making it essential for understanding the processing of HIV proteins. The importance of HIV protease in the maturation of infectious virus particles underscores its role as a target in the development of anti-AIDS therapies. By utilizing this substrate, you can effectively conduct continuous assays for HIV protease activity, supporting your research endeavors.
Key Features
- HiLyte Fluor 488 labeled for enhanced detection
- Derived from the critical p17/p24 cleavage site of HIV
- Facilitates continuous assays for HIV protease activity
- Supports research in HIV maturation and treatment
- Available in 0.1 mg quantities, ensuring ease of use
Specifications
| Property | Details |
|---|---|
| Peptide Sequence | GABA-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-EDANS |
| Labeling | HiLyte Fluor 488 |
| Quantity | 0.1 mg |
FAQ
What is the significance of the HIV substrate for protease activity?
This substrate mimics the natural cleavage site of the HIV polyprotein, enabling researchers to study the protease’s function and explore potential inhibitors.
How should I store the HIV Substrate, HiLyte™ Fluor 488?
It’s best to store it at -20°C to maintain its stability and effectiveness for your assays.
Can I use this substrate for other applications?
While it’s optimized for HIV protease assays, the substrate may also provide insights into related proteolytic processes in other viruses.
For those dedicated to HIV research, the HIV Substrate, HiLyte™ Fluor 488 is an indispensable addition to your toolkit. Consider exploring our other peptides to complement your experiments, including advanced options like PKG Substrate and Autocamtide-2. Start advancing your research today with this specialized substrate from AnaSpec.




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