IL-8 Inhibitor – 1 mg

Overview

The IL-8 Inhibitor is a powerful hexapeptide designed to inhibit the specific binding of 125I-IL-8 to neutrophils. This unique compound is acetylated on the amino terminus and amidated on the carboxyl terminus, making it an essential tool for your research in inflammation and immune response. IL-8, a member of the chemokine alpha subfamily, plays a crucial role in activating neutrophils and directing them to sites of inflammation. By blocking IL-8’s action, this peptide can enhance your understanding of neutrophil behavior and the mechanisms of various inflammatory conditions.

Key Features

• Inhibits specific binding of IL-8 to neutrophils
• Acetylated at the amino terminus for improved stability
• Amidated at the carboxyl terminus to enhance potency
• Vital for studying inflammatory responses and neutrophil activation
• Useful in researching macrophage inflammatory protein 2 (MIP 2) beta activity

Specifications

FAQ

What is the IL-8 Inhibitor used for?

The IL-8 Inhibitor is primarily used in research to study the mechanisms of inflammation, particularly in understanding how neutrophils respond to IL-8, which is critical in various inflammatory diseases.

How should I store the IL-8 Inhibitor?

For optimal stability, store the IL-8 Inhibitor powder at -20°C. Ensure that the container is tightly sealed to prevent moisture exposure.

Can the IL-8 Inhibitor also affect other chemokines?

While the primary action of the IL-8 Inhibitor is against IL-8, it has also been shown to suppress the binding of macrophage inflammatory protein 2 (MIP 2) beta to neutrophils, making it a valuable tool for related studies.

For additional peptide options, check out our selection of peptides that can complement your research. If you’re interested in exploring substrates, consider our PKG Substrate or the Autocamtide-2. Each of these products can serve as an important part of your experimental design.

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