Overview
Discover the unique properties of [Lys(Me1)36]-Histone H3 (26-46)-K(Biotin), a synthetic peptide that plays a significant role in epigenetic regulation. This peptide corresponds to amino acids 26 to 46 of the Schizosaccharomyces octosporus histone H3 and is notable for its monomethylation at lysine-36, a modification linked to RNA polymerase II (Pol II) elongation in Saccharomyces cerevisiae. The integration of biotin allows for versatile applications in assays and detection methods, making it an indispensable tool for researchers focusing on chromatin dynamics and gene expression pathways.
Key Features
- High purity of >95%, ensuring reliable performance in research applications.
- Monomethylated at lysine-36, crucial for studying histone modifications.
- Biotinylated for easy detection and labeling in various assays.
- Compatible with several detection methods including fluorescence and western blotting.
Specifications
| Product Name | Quantity |
|---|---|
| [Lys(Me1)36]-Histone H3 (26-46)-K(Biotin) | 1 mg |
FAQ
What is the significance of lysine-36 methylation?
Methylation at lysine-36 of histone H3 is a key modification associated with active gene transcription and is critical for the regulation of chromatin structure.
How can I use this peptide in my experiments?
This peptide can be utilized in various assays for studying histone modifications, protein-protein interactions, and chromatin dynamics. Its biotinylated form allows for easy detection using streptavidin-based methods.
Is this peptide suitable for in vivo studies?
While primarily designed for in vitro experiments, the peptide can be employed in certain in vivo contexts depending on your experimental design and application needs.
Add [Lys(Me1)36]-Histone H3 (26-46)-K(Biotin) to your research toolkit today and enhance your understanding of histone modifications. Explore our range of related products, including other peptides like Autocamtide-2 and assays for protein detection to complement your studies.
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