[Lys(Me1)4]-Histone H3 (1-21)-GGK(Biotin)

Name: [Lys(Me1)4]-Histone H3 (1-21)-GGK(Biotin) | AnaSpec
SKU: lysme14-histone-h3-1-21-ggkbiotin-27277e92-e701-415f-b38b-9f
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Price range: $162.00 through $422.00

[Lys(Me1)4]-Histone H3 (1-21)-GGK(Biotin). Histone 3 aa residues 1-21 mono-methylated at Lys-4 with C-terminal GG linker followed by biotinylated lysine.

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Clear

SKU: lysme14-histone-h3-1-21-ggkbiotin-27277e92-e701-415f-b38b-9f Category: Peptides Tags: biotin, histone, peptides

Overview

The [Lys(Me1)4]-Histone H3 (1-21)-GGK(Biotin) peptide is a specialized biochemical tool designed for researchers focusing on epigenetics and protein interactions. This peptide consists of the first 21 amino acid residues of Histone H3, featuring a mono-methylation at Lys-4, which is crucial for studying histone modifications in chromatin biology. Additionally, it is equipped with a C-terminal GG linker followed by a biotinylated lysine, facilitating easy detection and purification using streptavidin-based methods.

Key Features

High purity level of >95%, ensuring reliable experimental results.
Mono-methylation at Lys-4 for accurate modeling of histone modification.
Biotinylated for simple attachment to streptavidin for applications in various assays.
Provided in a lyophilized powder form, allowing for easy storage and handling.
Dissolved in distilled water at a concentration of 1 mg/ml to ensure optimal usage.

Specifications

Item	Details
Peptide Sequence	[Lys(Me1)4]-Histone H3 (1-21)-GGK
Purity	>95%
Form	Lyophilized powder
Storage	Store at -20°C

FAQ

What is the significance of mono-methylation at Lys-4 in Histone H3?

The mono-methylation at Lys-4 plays a vital role in gene regulation, influencing chromatin structure and transcriptional activity. It is a key modification studied in epigenetic research.

How do I use the [Lys(Me1)4]-Histone H3 peptide in my experiments?

This peptide can be utilized in various assays, including pull-down assays with streptavidin. It helps to investigate protein interactions and histone modifications relevant in cellular processes.

What are the storage requirements for this peptide?

For optimal stability, store the lyophilized peptide at -20°C. Once dissolved, it should be used within a few weeks and kept at -20°C to maintain activity.

Enhance your research with the [Lys(Me1)4]-Histone H3 (1-21)-GGK(Biotin) peptide. Available now for purchase, this product is essential for those studying histone modifications and their implications in various biological processes. Don’t miss out on this opportunity to equip your lab with high-quality reagents. Shop today at AnaSpec!