Protease-Activated Receptor-3, PAR-3 Agonist, amide – 1 mg

Overview

The Protease-Activated Receptor-3 (PAR-3) Agonist, amide, is a high-affinity thrombin receptor that plays a crucial role in various physiological responses. Found predominantly in the cutaneous mast cells of humans, PAR-3 mRNA expression indicates its significance in mediating interactions with thrombin. Unlike some of its counterparts, PAR-3 doesn’t induce itching by itself but may influence responses when acting alongside PAR-4. This unique property underlines its potential in research focusing on itch mechanisms and related pathways.

Key Features

• High-affinity agonist for thrombin receptor PAR-3
• Critical for studying skin-related physiological responses
• Supports research on itch mechanisms
• Provides insights into the co-expression with PAR-4
• Available in a convenient 1 mg format

Specifications

FAQ

What is the role of PAR-3 in research?

PAR-3 is significant for studying its interactions with thrombin and its involvement in physiological processes, particularly in relation to itch responses and mast cell functions.

How is this PAR-3 Agonist typically used?

This agonist is often utilized in laboratory settings to explore its effects on thrombin action and its interactions with other receptors, especially PAR-4.

Can this product help in itch-related studies?

Yes, while PAR-3 alone does not induce itch, it can influence itch mechanisms when studied in conjunction with PAR-4, making it valuable for itch-related research.

To complement your research on protease-activated receptors, consider our PKG Substrate or check out our range of peptides for other related products that may enhance your findings.

Related Products

• Autocamtide-2 [KKALRRQETVDAL]
• CREBtide [KRREILSRRPSYR], 5-FAM labeled