ß-Secretase Inhibitor 1 – 1 mg

Overview

The ß-Secretase Inhibitor 1 (1 mg) is a potent statine-based substrate analog specifically designed to inhibit the action of beta-secretase (BACE1), a critical enzyme involved in the production of Aß peptides. These peptides are known for their role in the formation of amyloid plaques, a hallmark of Alzheimer’s disease (AD). By targeting BACE1, this inhibitor offers a promising avenue for anti-amyloid therapies, making it an essential tool for researchers focusing on neurodegenerative diseases.

Key Features

• Highly effective beta-secretase inhibitor
• Statine-based substrate analog for optimal specificity
• Valid for use with homogenized wild-type mouse cortices
• Compatible with BACE-purified enzymes from human brain samples
• Supports research in Alzheimer’s disease and related conditions

Specifications

FAQ

What is the mechanism of action for ß-Secretase Inhibitor 1?

This inhibitor works by mimicking the natural substrate of BACE1, thus preventing the enzyme from cleaving its actual substrates that lead to the formation of potentially harmful Aß peptides.

How should I store ß-Secretase Inhibitor 1?

For optimal stability, store this inhibitor at -20°C, protected from light and moisture. Once reconstituted, it should be used promptly to ensure efficacy.

Where can I find more related products?

You can explore our complete range of peptides, including other inhibitors and substrates, by visiting our peptides category.

With its precise formulation and targeted impact, ß-Secretase Inhibitor 1 is essential for advancing Alzheimer’s research. Order now and take a step toward unlocking new therapeutic strategies in cognitive health.

Related Products

• PKG Substrate [RKRSRAE], Glasstide
• Autocamtide-2 [KKALRRQETVDAL]
• CREBtide [KRREILSRRPSYR], 5-FAM labeled