[Arg(Me2s)8]-Histone H3 (1-21)-K(Biotin) – 1 mg

Overview

Introducing [Arg(Me2s)8]-Histone H3 (1-21)-K(Biotin) – a unique biotinylated peptide that plays a critical role in epigenetic research. This peptide is symmetrically dimethylated at Arg8, featuring a methyl group on each nitrogen of the guanidinium group. Designed for researchers seeking precise modulation of histone modifications, it is particularly valuable for studies involving gene expression regulation and chromatin dynamics.

Key Features

• Biotinylated at the epsilon side chain of the C-terminal Lys
• Symmetrically dimethylated at Arg8, inhibiting G9a methylation of Lys9
• High purity of over 95% to ensure reliable results
• Available as a lyophilized powder, easily reconstituted in distilled water
• Essential for assays and experiments focusing on gene regulation

Specifications

FAQ

What is the significance of methylation at Arg8?

Methylation at Arg8 is crucial as it prevents G9a from methylating Lys9, which is a key step in histone modification and gene regulation.

How do I reconstitute the peptide?

To reconstitute the [Arg(Me2s)8]-Histone H3 (1-21)-K(Biotin), simply dissolve the lyophilized powder in distilled water to achieve a concentration of 1 mg/ml.

Can I use this peptide for my assays?

Yes, this biotinylated peptide is ideal for assays focused on histone modifications and can be a valuable tool in your research.

For those interested in further enhancing their assays, consider exploring options like our PKG Substrate or the innovative Autocamtide-2. You may also find our CREBtide beneficial for your peptide needs. Don’t forget to check our full range of peptides to discover more options for your research.