Histone H4 (1-21), p300/CBP Substrate – 1 mg

Overview

Histone H4 (1-21), p300/CBP Substrate is a critical peptide for researchers focusing on histone modifications, particularly acetylation. This peptide represents the first 21 amino acids of Histone H4, specifically designed for studying interactions with histone acetyltransferase (HAT) p300/CBP. The p300/CBP enzyme is known for catalyzing the acetylation of free histone H4, which plays a pivotal role in gene expression regulation and chromatin remodeling. This substrate is essential for experiments aimed at understanding these epigenetic mechanisms and their implications in various biological processes.

Key Features

• Contains amino acids 1 to 21 of Histone H4
• Facilitates studies on acetylation by p300/CBP
• Optimal for in vitro assays related to histone modifications
• Highly pure and well-characterized for consistent results
• Supports a variety of applications in biochemical research

Specifications

FAQ

What is the primary use of Histone H4 (1-21), p300/CBP Substrate?

This peptide is primarily used in biochemical assays to study the acetylation process mediated by p300/CBP, providing insights into gene regulation.

How does this substrate assist in research?

By using Histone H4 (1-21) as a substrate, researchers can analyze the acetylation patterns at specific lysine residues, which are critical for understanding epigenetic modifications.

Is this peptide suitable for both in vitro and in vivo studies?

This substrate is optimized for in vitro studies, making it ideal for laboratory settings focusing on histone modifications.

For more applications in peptide studies, explore our range of related products, including PKG Substrate and Autocamtide-2. If you’re interested in fluorescent applications, take a look at CREBtide, 5-FAM labeled. Visit our Peptides category for more options. Make your purchase today and advance your research with this essential substrate.