Overview
The IKKgamma NEMO Binding Domain (NBD) Inhibitory Peptide is a vital tool for researchers investigating the complex mechanisms of NF-kB signaling. This cell-permeable synthetic peptide effectively blocks TNF-alpha-induced NF-kB activation, making it essential for studies focused on inflammation and cellular responses. By targeting the NEMO-binding domain, this peptide interrupts the interaction between IKγNEMO and the IKK complex, which is crucial for NF-kB activation.
Key Features
- Cell-permeable synthetic peptide
- Blocks TNF-alpha-induced NF-kB activation
- Targets the NEMO amino-terminal alpha-helical region
- Ideal for studying inflammatory pathways and cellular responses
- Convenient 1 mg quantity for various experimental applications
Specifications
| Property | Detail |
|---|---|
| Product Name | IKKgamma NEMO Binding Domain (NBD) Inhibitory Peptide |
| Form | Powder |
| Quantity | 1 mg |
| Category | Peptides |
FAQ
What applications can I use the IKKgamma NBD Inhibitory Peptide for?
This peptide is designed for research related to NF-kB signaling pathways, particularly in studies examining how TNF-alpha impacts cellular responses and inflammation.
How should I store the IKKgamma NBD Inhibitory Peptide?
For optimal stability, store the peptide at -20°C. Ensure it’s in a dry environment and protected from light to maintain its integrity.
Can I integrate this peptide with other assays?
Yes, you can integrate the IKKgamma NBD Inhibitory Peptide with various assays, including those involving PKG Substrate and Autocamtide-2to further explore the role of NF-kB in cellular activities.
This peptide is an essential addition to your research toolkit. With the IKKgamma NBD Inhibitory Peptide, you gain a powerful resource for delving into the nuances of NF-kB signaling. Purchase yours today and enhance your research capabilities with a peptide that delivers on its promise of performance.
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