Myristolated PKCz, Pseudosubstrate (ZIP) – 1 mg

Overview

The Myristolated PKCζ, Pseudosubstrate (ZIP) is a specialized peptide designed for researchers focused on Protein Kinase C interactions. This peptide is derived from the pseudosubstrate region of the N-terminal regulatory domain of PKCζ, which keeps the kinase in its inactive state in the absence of activators. The unique myristoylation enhances membrane association and specificity, making it invaluable for studying PKC-dependent signaling pathways. Researchers will find this peptide particularly useful for probing the roles of atypical Protein Kinase Cζ in cellular mechanisms, as well as its interactions with other PKC family isoforms.

Key Features

• Inhibitory action on atypical PKCζ, allowing for detailed studies of signaling pathways.
• Myristoylation enhances membrane affinity, providing better cellular context.
• Interacts with multiple PKC isoforms, expanding its utility in various research applications.
• Supports studies on physiological memory impairment, linking PKC activity to cognitive function.

Specifications

FAQ

What research applications is the Myristolated PKCζ, Pseudosubstrate (ZIP) suited for?

This peptide is ideal for studying PKCζ inhibition, signaling pathways, and their implications in memory functions. It’s useful for researchers examining various aspects of PKC isoform interactions.

How does myristoylation affect the PKCζ peptide’s performance?

Myristoylation increases the hydrophobicity of the peptide, enhancing its ability to associate with cell membranes, which is critical for studying PKC’s native biochemical environment and functionality.

Can I use this peptide for cellular studies?

Yes, the Myristolated PKCζ, Pseudosubstrate (ZIP) is suitable for cellular studies that investigate the activity and translocation of PKC isozymes, making it a versatile tool for exploring kinase-related functions.

For additional insights into peptide research, check out our collection of peptides to find more options that can enhance your studies. If you’re looking for a more specific substrate, consider our PKG Substrate or the Autocamtide-2 for diverse applications. The Myristolated PKCζ, Pseudosubstrate (ZIP) offers a unique way to further your investigation into protein kinases.

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