AKT/PKB/Rac-Protein Kinase Substrate [ARKRERTYSFGHHA], Biotinylated

Name: ARKRERTYSFGHHA Biotinylated Peptide | AnaSpec
SKU: aktpkbrac-protein-kinase-substrate-arkrertysfghha-biotinylat
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The native peptide ARKRERTYSFGHHA (29944-1) is a synthetic substrate for AKT/PKB/Rac-protein kinases. Phophorylation is at the Ser site (Km = 3.9 µM). It also competitively inhibits histone H2B phosphorylation (Ki = 12 µM) by AKT.

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SKU: aktpkbrac-protein-kinase-substrate-arkrertysfghha-biotinylat Category: Peptides Tags: biotinylated peptides, peptide research, protein substrates

Overview

The biotinylated peptide ARKRERTYSFGHHA (29944-1) serves as a synthetic substrate specifically designed for AKT/PKB/Rac-protein kinases. This peptide is essential for researchers exploring phosphorylation processes, particularly at the Ser site, with an affinity constant (Km) of 3.9 µM. Its unique design also allows it to competitively inhibit histone H2B phosphorylation by AKT, boasting an inhibition constant (Ki) of 12 µM.

As you work on your studies or projects, consider integrating ARKRERTYSFGHHA into your assays to gain insights into protein kinases’ functions. Discover other innovative products such as PKG Substrate [RKRSRAE] or Autocamtide-2 [KKALRRQETVDAL] to enhance your research further.

Key Features

Biotinylated for easy detection and isolation
Specific substrate for AKT/PKB/Rac-protein kinases
Phosphorylation site at Ser with Km = 3.9 µM
Competes with histone H2B phosphorylation (Ki = 12 µM)
Ideal for various biochemical assays and studies

Specifications

Product Name	ARKRERTYSFGHHA (29944-1)
Modification	Biotinylated
Application	AKT/PKB/Rac-protein kinase substrate
Phosphorylation Site	Ser
Km	3.9 µM
Ki	12 µM

FAQ

What is the application of ARKRERTYSFGHHA?

ARKRERTYSFGHHA is used as a substrate for AKT/PKB/Rac-protein kinases in various biochemical assays, providing critical insights into kinase activity.

How does the biotinylation help in experiments?

The biotinylation of ARKRERTYSFGHHA allows for easy detection and isolation using streptavidin-coated surfaces or beads, enhancing experimental efficiency.

What are the storage conditions for this peptide?

Store ARKRERTYSFGHHA at -20°C for long-term stability. Avoid repeated freeze-thaw cycles to maintain its efficacy.

For a comprehensive selection of peptides, explore our Peptides collection. Each product is crafted to meet your research needs. Start enhancing your research endeavors with ARKRERTYSFGHHA today.