[Trp63, 64]-C3a (63-77) – 1 mg

Overview

[Trp63, 64]-C3a (63-77) is a specialized C-terminal analogue of the complement factor C3a, designed for research applications that require precise interaction with the C3a receptor. By acting as a selective agonist, this peptide plays a crucial role in studies of immune response and inflammatory processes. Derived from the essential fifteen C-terminal residues of C3a, [Trp63, 64]-C3a has been shown to bind effectively to C3a receptors, making it a valuable tool for laboratories focused on immune signaling.

Key Features

• Analogue of complement factor C3a for selective receptor binding
• Induces degranulation of C3aR-transfected cells
• Demonstrated hypertensive response in vivo in rat models
• Useful for research in immunology and inflammation
• Available in a 1 mg format for convenient use

Specifications

Product Name	[Trp63, 64]-C3a (63-77)
Category	Peptides
Quantity	1 mg

FAQ

What is [Trp63, 64]-C3a used for?

[Trp63, 64]-C3a is primarily used in research to study its role as an agonist for the C3a receptor, which is important in immune signaling and inflammation.

How does [Trp63, 64]-C3a interact with C3a receptors?

In vitro studies have demonstrated that [Trp63, 64]-C3a selectively binds to C3a receptors and can induce cellular degranulation, providing insights into its functional capabilities.

Is this peptide suitable for in vivo studies?

Yes, studies in rat models have shown that [Trp63, 64]-C3a can induce a transient hypertensive response, indicating its potential for in vivo applications and further research.

If you’re conducting research in immunology or inflammation, consider adding [Trp63, 64]-C3a (63-77) to your lab’s toolkit. For related products, check out our PKG substrateAutocamtide-2or explore our extensive range of peptides to enhance your research capabilities.

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